Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06964568 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

CCRT Followed by PD-1 Inhibitor Maintenance Therapy in Locally Advanced ESCC

StatusRecruiting
PhasePhase 3
Started2025-02-01
View on ClinicalTrials.gov ↗

Amendment history

2026-04-14
Study Status, Arms and Interventions, Outcome Measures v3
Trial arms changed: 2 → 4
InterventionsPD-1 inhibitor (Drug), Radiotherapy (Radiation), TP regimen (Drug)→PD-1 inhibitor (Drug), TDLN-sparing radiotherapy (Radiation), TP regimen (Drug), Unlimited radiotherapy (Radiation)
Secondary endpoints3 to 4 entries
OS
2026-02-06
Study Identification, Study Status, Study Description, Arms and Interventions, Outcome Measures v2
Study arms4→2
InterventionsPD-1 inhibitor (Drug), TDLN-sparing radiotherapy (Radiation), Unlimited radiotherapy (Radiation)→PD-1 inhibitor (Drug), Radiotherapy (Radiation), TP regimen (Drug)
Secondary endpoints2 to 3 entries
PFS
Primary endpoints2 to 1 entries
PFS
Study title-11 characters
TDLN-sparing RTCCRT Followed by PD-1 Inhibitor Maintenance Therapy in Locally Advanced ESCC
2026-01-05
Study Status v1
Re-verified, no change to tracked fields
2025-05-01
Original filing
The goal of this clinical trial is to learn if concurrent chemoradiotherapy followed by immunotherapy as maintenance therapy works to treat locally advanced esophageal squamous cell cancer in adults.
Trial Details
NCT Number NCT06964568
Lead Sponsor Fudan University
Conditions Esophageal Carcinoma, Radiotherapy, Immunotherapy
Enrollment 452 participants
Start Date 2025-02-01
Primary Completion 2029-02 (estimated)
Study Completion 2031-02 (estimated)
Updated on ClinicalTrials.gov 2026-04-17