Clinical Trial

rTMS as Add on Treatment for Substance Use Disorders

Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated June 29, 2025 (before its estimated May 2026 completion). Its status may not reflect the trial's current state.
Summary
This pilot study is designed to test feasibility and superiority of rTMS types and target locations for the optimal rTMS intervention for individuals seeking treatment for Alcohol Use Disorder (AUD) or Opioid Use Disorder (OUD). The critical questions this study seeks to answer are: which rTMS type applied to l-dlPFC in OUD participants will induce the greatest reduction of opioid use post-treatment? Is inhibitory rTMS applied to medial prefrontal cortex (mPFC) more effective than excitatory rTMS applied to l-dlPFC at reducing alcohol use post treatment in AUD participants?
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-05-06; most recent amendment 2025-06-27.
Status change: Not Yet Recruiting → Recruiting 2025-06-27
Trial Details
NCT Number NCT06963476
Lead Sponsor Yale University
Conditions Opioid Use, Alcohol Use Disorder
Enrollment 80 participants
Start Date 2025-05-12
Primary Completion 2026-05 (estimated)
Study Completion 2026-05 (estimated)
Updated on ClinicalTrials.gov 2025-06-29