First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.

Non randomized study with two groups. The study group includes patients with suspected malignant pleural effusion, in whom the investigation of pleural effusion begins directly with pleural biopsy by Local Anesthesia Thoracoscopy (LAT). The Control Group includes patients who come to the same hospital and are treated with the Standard of Care (SOC) strategies were used. Efficacy of LAT, Sensitivity, Hospitalization, time to diagnosis and general safety and comfort of the groups' subjects will be assessed.

NCT Number	NCT06946498
Lead Sponsor	National and Kapodistrian University of Athens Collaborators: Sotiria Thoracic Diseases Hospital of Athens
Conditions	Suspected Malignant Lung Neoplasm, Pleural Effusion, Pleural Effusion, Malignant, Mesothelioma, Malignant
Enrollment	100 participants
Start Date	2023-05-23
Primary Completion	2025-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-04-27