Clinical Trial

A Study to Investigate the Impact of Multiple Doses of Itraconazole on AZD5004 in Healthy Participants and Multiple Doses of AZD5004 on Combined Oral Ethinyl Oestradiol and Levonorgestrel in Healthy Female Participants

Completed Phase 1
View on ClinicalTrials.gov →
Summary
The purpose of this study is to assess the impact of multiple doses of itraconazole on the pharmacokinetics (PK) of AZD5004 in healthy participants (Part A), and to assess the impact of multiple doses of AZD5004 on the PK of Combined Oral Contraceptives (COCs) in healthy female participants (Part B).
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2025-04-17; most recent amendment 2026-02-02.
Status change: Active, Not Recruiting → Completed 2026-02-02
Status change: Recruiting → Active, Not Recruiting 2025-12-11
Status change: Not Yet Recruiting → Recruiting 2025-06-24
Trial Details
NCT Number NCT06942936
Lead Sponsor AstraZeneca
Collaborators: Parexel
Conditions Healthy Participants
Enrollment 51 participants
Start Date 2025-05-28
Primary Completion 2026-01-28 (estimated)
Study Completion 2026-01-28 (estimated)
Updated on ClinicalTrials.gov 2026-02-03