Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASIL

The project aims to retrospectively and prospectively analyze a population of CADASIL patients in order to study the natural history of the disease by correlating the symptom spectrum with genetic risk and specific neuroradiological and biological markers \- Stratifying patients according to their disease risk, this could contribute to the discovery of personalized therapeutic targets.

NCT Number	NCT06938100
Lead Sponsor	Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Conditions	CADASIL, CADASIL (Diagnosis)
Enrollment	100 participants
Start Date	2023-11-21
Primary Completion	2027-04-30 (estimated)
Study Completion	2027-10-31 (estimated)
Updated on ClinicalTrials.gov	2025-04-22