Clinical Trial

Subcortical Arousal in Perceptual Awareness

Recruiting
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Summary
The study consists of prospective enrollment of healthy participants and patients with epilepsy, as well as analysis of an existing data set. Healthy participants will be studied with fMRI, eye metrics and behavioral testing at Yale. Patients will be studied with intracranial thalamic and cortical recording and stimulation, eye metrics and behavioral testing.
Protocol Amendment History 3 changes
critical Primary endpoint(s) modified 2026-05-07
notable Enrollment increased: 72 -> 202 participants 2026-05-07
minor Trial arms changed: 2 -> 3 2026-05-07
Trial Details
NCT Number NCT06934356
Lead Sponsor Yale University
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)
Conditions Epilepsy
Enrollment 202 participants
Start Date 2025-10-13
Primary Completion 2030-12 (estimated)
Study Completion 2030-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-10