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MPFL Reconstruction Versus Rehabilitation

Study acronym: ANTI-GLIDE
StatusWithdrawn
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Stopped Withdrawn before enrolling Sponsor's reason: No participants recruited Enrollment target: estimated 30 to confirmed 0 · Primary completion date changed from estimate of Dec 31, 2027 to Oct 5, 2026 · Eligibility criteria expanded, about 15 words · 1 more Show 4 more changesShow less
    • Enrollment target: estimated 30 to confirmed 0
    • Primary completion date changed from estimate of Dec 31, 2027 to Oct 5, 2026
    • Eligibility criteria expanded, about 15 words
    • Secondary endpoints: details revised at 3 of 6 entries
  2. Notable Primary and study completion dates: Jun 1, 2027 to Dec 31, 2027 Start date: Jun 1, 2025 to Jan 1, 2026 · Secondary endpoints: details revised at 1 of 6 entries · Study description revisedv2 Show 3 more changesShow less
    • Start date: Jun 1, 2025 to Jan 1, 2026
    • Secondary endpoints: details revised at 1 of 6 entries
    • Study description revised

    See this version in full on ClinicalTrials.gov ↗

  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study involves patients between the ages of 16 and 25 and have been diagnosed with a first-time traumatic patellar dislocation within the past 3 months. McMaster University and the investigators are receiving compensation from the Arthroscopy Association of North America to cover the costs of conducting the study. Dislocations of the kneecap or patella is often treated without surgery, however up to 50% of patients will unfortunately experience recurrent instability of the patella. These episodes can cause damage to the bones and cartilage in the knee, which can result in long-term knee pain or weakness. Therefore, there is increasing interest to consider treating the knee with surgery right away in this population. The purpose of this study is to determine the effect of medial patellofemoral ligament (MPFL) reconstruction compared to rest and physical rehabilitation on the rate of repeat patella dislocation, pain, and knee function for patients with their first patellar dislocation. The investigators will follow patients for at least one year after assigned treatment is started. Outcomes will be measured using surveys and checking medical records over the course of the study. The pilot will test this research study on a smaller scale before conducting a larger study. Patients will not be asked to attend additional visits outside of their typical follow-up schedule with their doctor. There will be 30 patients recruited in total for this pilot study. Not all patients diagnosed with a patellar dislocation will be eligible to participate. Participation will be required at 6 regularly scheduled appointments that patients would need to attend to see the surgeon (even if they were not in the trial), including the screening visit, surgery date (if randomized to that treatment), 2-week, 6-week, 3-month, 6-month, and 12-month follow-up visits. Patients will be asked how they feel via various questionnaires and should take no longer than 15-20 minutes to complete the research forms at each visit. If patients agree to participate in this study, treatment will be determined by a process called randomization. Randomization means that the treatment the patient receives will be decided by chance like flipping a coin. Patients will have a 1-in-2 chance of receiving one of the following treatments:
Trial Details
NCT Number NCT06926699
Lead Sponsor McMaster University
Collaborators: Arthroscopy Association of North America
Conditions Patellar (or Kneecap) Instability and Mal-alignment, Patellar Dislocation
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov