Clinical Trial

PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy

Study acronym: PEACE
Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
This randomized controlled trial compares two common medications, labetalol and extended-release nifedipine, to determine which is more effective at managing postpartum high blood pressure. We hypothesize that extended-release nifedipine will better control blood pressure and reduce the need for continued medication beyond six weeks postpartum. The study will enroll 110 postpartum participants, randomly assigning them to one of the two medications, with remote blood pressure monitoring to evaluate treatment effectiveness and inform postpartum hypertension management.
Trial Details
NCT Number NCT06915792
Lead Sponsor University of California, Los Angeles
Conditions Postpartum Hypertension (PPHT)
Enrollment 110 participants
Start Date 2025-06-01
Primary Completion 2027-07-31 (estimated)
Study Completion 2027-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-05