PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy

This randomized controlled trial compares two common medications, labetalol and extended-release nifedipine, to determine which is more effective at managing postpartum high blood pressure. We hypothesize that extended-release nifedipine will better control blood pressure and reduce the need for continued medication beyond six weeks postpartum. The study will enroll 110 postpartum participants, randomly assigning them to one of the two medications, with remote blood pressure monitoring to evaluate treatment effectiveness and inform postpartum hypertension management.

NCT Number	NCT06915792
Lead Sponsor	University of California, Los Angeles
Conditions	Postpartum Hypertension (PPHT)
Enrollment	110 participants
Start Date	2025-06-01
Primary Completion	2027-07-31 (estimated)
Study Completion	2027-10-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-05