Clinical Trial

Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants

Terminated Phase 1
View on ClinicalTrials.gov →
Why the trial stopped
Business Decision
Summary
The main objective of the study is to assess the safety and tolerability of AMG 378 as single or multiple doses in healthy participants.
Protocol Amendment History 2 changes
notable Primary completion moved earlier: 2026-01-21 -> 2025-12-02 2026-04-03
minor Completion moved earlier: 2026-01-21 -> 2025-12-02 2026-04-03
Trial Details
NCT Number NCT06910709
Lead Sponsor Amgen
Conditions Healthy Volunteers
Enrollment 48 participants
Start Date 2025-04-08
Primary Completion 2025-12-02 (estimated)
Study Completion 2025-12-02 (estimated)
Updated on ClinicalTrials.gov 2026-04-02