Assessing Chest Pain Using Point-of-Care High-Sensitivity Troponin I in the Emergency Department

The goal of this proposal is to improve the quality and value of care for patients with acute chest pain by investigating the potential impact of point-of-care (POC) high sensitivity cardiac troponin (hs-cTn) testing in the Emergency Department (ED) and exploring how best to integrate POC hs-cTnl into ED risk stratification workflows. The study hypothesizes that the Abbott i-STAT POC hs-cTnI assay will decrease time-to-result (TTR) and ED length of stay (LOS), while increasing ED revenue for patients with acute chest pain compared to a strategy of central laboratory hs-cTnI testing.

NCT Number	NCT06899776
Lead Sponsor	Wake Forest University Health Sciences Collaborators: Abbott Point of Care
Conditions	ACS (Acute Coronary Syndrome)
Enrollment	600 participants
Start Date	2025-02-07
Primary Completion	2025-09-15 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2026-07-29