Clinical Trial

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the blood pressure. This study will evaluate blood samples for renin concentration throughout the course of open heart surgery.
Protocol Amendment History 3 changes
critical Enrollment closed, study ongoing 2026-08-11
notable Primary completion pushed: 2026-07 -> 2026-12 2026-08-11
minor Completion pushed: 2026-07 -> 2026-12 2026-08-11
Trial Details
NCT Number NCT06895213
Lead Sponsor Mayo Clinic
Conditions Cardiac Surgery With Cardiopulmonary Bypass
Enrollment 100 participants
Start Date 2025-04-14
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-10