Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: the ADVICE Protocol Study (Phase 2)

This phase of the project aims to compare in-person, supervised educational programs (EP) with online self-guided EPs in individuals with relapsing-remitting multiple sclerosis. A total of 75 participants will be randomly assigned to one of three groups: a supervised and individualized educational program focused on HIIT training, a supervised and individualized educational program focused on strength training, and a non-supervised, self-guided educational program based on resistance band training. Additionally, sessions on the Mediterranean diet (both supervised and non-supervised) and cognitive-behavioral interventions will be included. A control evaluation will be conducted three months after the intervention to assess the effects of the educational programs, followed by another evaluation three months later to analyze residual effects. Women who participated in Phase 1 of the study will be invited to take part in this second phase.

NCT Number	NCT06884579
Lead Sponsor	Universidad de Almeria Collaborators: Hospital Universitario Virgen de la Arrixaca
Conditions	Multiple Sclerosis (MS) - Relapsing-remitting
Enrollment	60 participants
Start Date	2025-04-15
Primary Completion	2025-06-15 (estimated)
Study Completion	2026-07-28 (estimated)
Updated on ClinicalTrials.gov	2026-03-24