Clinical Trial

Relationship of Point-of-care Coagulation Assays with Clinical Outcomes in Cardiac Surgery: a Retrospective Cohort Study

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Record status
This record was last updated March 19, 2025 (before its estimated March 15, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to determine the relationship of ROTEM point-of-care coagulation assay parameters with excessive bleeding and clinical outcomes in patients undergoing cardiac surgery at Toronto General Hospital. The main questions it aims to answer are: i) How well does viscoelastic testing (VET) predict the clinical outcome of excessive bleeding in cardiac surgery? ii) Which VET parameters have the greatest accuracy for identification of patients who will have excessive bleeding? iii) 3) What is the prognostic value of abnormal VET parameters with other clinical outcomes after cardiac surgery?
Trial Details
NCT Number NCT06882759
Lead Sponsor University Health Network, Toronto
Conditions Cardiac Surgery Requiring Cardiopulmonary Bypass
Enrollment 15,000 participants
Start Date 2025-03-15
Primary Completion 2026-03-15 (estimated)
Study Completion 2026-03-15 (estimated)
Updated on ClinicalTrials.gov 2025-03-19