Clinical Trial

Comparison of Single vs. Dual Perclose Devices for Large-Bore Access Closure in TAVR

Recruiting
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Summary
This study will compare the use of one Perclose device to the usual approach of two devices for pre-closure during Transcatheter Aortic Valve Replacement (TAVR). The study will compare the time it takes for bleeding to stop using the different closure approaches. The study will also compare complications when using one Perclose device versus two.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-06 -> 2027-06 2026-06-26
minor Completion pushed: 2026-07 -> 2027-06 2026-06-26
Trial Details
NCT Number NCT06871774
Lead Sponsor Wake Forest University Health Sciences
Conditions Transcatheter Aortic Valve Replacement
Enrollment 300 participants
Start Date 2025-06-16
Primary Completion 2027-06 (estimated)
Study Completion 2027-06 (estimated)
Updated on ClinicalTrials.gov 2026-06-25