Clinical Trial

Pre-malignant States to Hematologic Malignancies in Firefighters

Recruiting
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Summary
The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic malignancies, and potentially other pathophysiological consequences.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2025-03-05; most recent amendment 2026-07-10.
Status change: Not Yet Recruiting → Recruiting 2025-05-05
Trial Details
NCT Number NCT06870760
Lead Sponsor Wake Forest University Health Sciences
Collaborators: Atrium Health Levine Cancer Institute
Conditions Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia, Multiple Myeloma, Plasma Cell Disorder
Enrollment 300 participants
Start Date 2026-06-23
Primary Completion 2027-04 (estimated)
Study Completion 2027-04 (estimated)
Updated on ClinicalTrials.gov 2026-07-13