Clinical Trial

Patiromer and Diet/hrQoL in Chronic Dialysis

Study acronym: PRINCE
Recruiting Phase 3
View on ClinicalTrials.gov →
Record status
This record was last updated September 4, 2025 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.
Summary
This is a phase III, prospective, randomized, double-blind, placebo-controlled, single-center, pilot trial, aimed at assessing whether treatment with the oral potassium binder patiromer as compared to placebo allows withdrawal or down-titration of potassium dietary restriction without increasing the risk of hyperkalemia in chronic dialysis patients.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-02-27; most recent amendment 2025-08-27.
Status change: Not Yet Recruiting → Recruiting 2025-08-27
Trial Details
NCT Number NCT06858280
Lead Sponsor Mario Negri Institute for Pharmacological Research
Conditions Hyperkalaemia, Chronic Kidney Disease Stage 3 and 4, Dietary Intervention
Enrollment 40 participants
Start Date 2025-07-08
Primary Completion 2026-07 (estimated)
Study Completion 2026-07 (estimated)
Updated on ClinicalTrials.gov 2025-09-04