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Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis

StatusRecruiting
PhasePhase 2
Started
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Record History

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  1. Minor Re-verified, no change to tracked fieldsv5
  2. Notable Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 0 to 1
    • Start date changed from estimate of Apr 2025 to Jun 1, 2025
    v4
  3. Minor Secondary endpoints: details revised at 1 of 1 entryv3
  4. Minor Secondary endpoints: details revised at 1 of 1 entry
    • Study description expanded, about 1 word
    v2
  5. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study will assess the safety and efficacy of topical ruxolitinib for treating the refractory cutaneous manifestations in patients with dermatomyositis. The investigators' hypothesis is that topical ruxolitinib will be both safe and effective for such patients.
Trial Details
NCT Number NCT06857240
Lead Sponsor The Cleveland Clinic
Conditions
(from sponsor)
Dermatomyositis
Related terms Dermatomyositis
Enrollment 15 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov