Radiotherapy of Head and Neck Cancer With SIB

Title: Simultaneous Integrated Boost in Primary and Adjuvant Therapy of Head and Neck Tumors: Quality Control Registry Prospective Longitudinal Observational Study Short Title: Radiotherapy for Head and Neck Tumors with SIB Objective: To evaluate the efficacy and safety of definitive and adjuvant radio(chemo)therapy with simultaneous integrated boost (SIB) in patients with head and neck cancers. The study aims to assess local and regional control, overall survival, metastasis-free survival, therapy-related toxicities, and quality of life. Study Design: A prospective, longitudinal, non-interventional registry study documenting real-world outcomes and quality measures of therapy applied according to existing clinical guidelines.

NCT Number	NCT06831903
Lead Sponsor	Wuerzburg University Hospital
Conditions	Quality of Life (QOL), Head and Neck Cancer, Radiotherapy Side Effect, Radiotherapy, Conformal (IMRT)
Enrollment	750 participants
Start Date	2019-05-21
Primary Completion	2034-10-01 (estimated)
Study Completion	2039-10-01 (estimated)
Updated on ClinicalTrials.gov	2025-02-18