Clinical Trial

A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion

Study acronym: IOPT
Recruiting Phase 2
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Summary
In the present study, we aim to investigate the efficacy and safety of concurrent therapy of Immunotherapy based combination therapy and Radiotherapy in patients with advanced HCC showing macrovascular invasion.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-02-10; most recent amendment 2025-12-24.
Status change: Not Yet Recruiting → Recruiting 2025-04-18
Trial Details
NCT Number NCT06828380
Lead Sponsor National Cancer Center, Korea
Conditions Advanced Hepatocellular Carcinoma (HCC)
Enrollment 128 participants
Start Date 2025-04-15
Primary Completion 2028-08-06 (estimated)
Study Completion 2028-08-06 (estimated)
Updated on ClinicalTrials.gov 2025-12-26