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Calcium Administration in Life-saving Management During Massive Hemorrhage

Study acronym: CALM
StatusNot Yet Recruiting
PhasePhase 2/3
Started2025-05-01
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 11, 2025 (before its estimated April 30, 2026 completion). Its status may not reflect the trial's current state.
This study evaluates the feasibility of conducting a larger study on the impact of treating massive hemorrhage with calcium in trauma patients. Patients undergoing the Massive Hemorrhage Protocol (MHP) will be randomly assigned to receive either calcium gluconate or placebo drug after every 4 packs of units of RBCs received during the MHP.
Trial Details
NCT Number NCT06820645
Lead Sponsor London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions Massive Hemorrhage, Trauma, Hypocalcemia
Enrollment 81 participants
Start Date 2025-05-01
Primary Completion 2026-04-30 (estimated)
Study Completion 2026-05 (estimated)
Updated on ClinicalTrials.gov 2025-02-11