Clinical Trial

Neoadjuvant FOLFIRINOX and Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer Patients

Recruiting Phase 2
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Summary
A phase II clinical trial compared standard TNT (mFolfox6 and CRT) with preoperative chemoradiotherapy (CRT) with neoadjuvant chemotherapy (CT) containing mFolfirinox in patients with locally advanced rectal cancer.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-02-01.
Trial Details
NCT Number NCT06812728
Lead Sponsor Menoufia University
Conditions Rectum Cancer
Enrollment 100 participants
Start Date 2025-01-25
Primary Completion 2027-01-25 (estimated)
Study Completion 2027-02-25 (estimated)
Updated on ClinicalTrials.gov 2025-02-19