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A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

Name: A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis — clinical trial record (NCT06807424)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: ICONIC-PsA 2

StatusRecruiting

PhasePhase 3

SponsorJanssen Research & Development, LLC

Started2025-01-09

View on ClinicalTrials.gov ↗

The purpose of this study is to evaluate the efficacy of icotrokinra (JNJ-77242113) compared to placebo in biologic-experienced and biologic-naive participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.

Amendment history 3 changes detected by DataLookout

2026-08-29

Trial sites expanded: 233 → 236 locations

2026-08-01

Trial sites expanded: 224 → 233 locations

2026-07-07

Trial sites expanded: 216 → 224 locations

Trial Details

NCT Number	NCT06807424
Lead Sponsor	Janssen Research & Development, LLC
Conditions	Arthritis, Psoriatic
Enrollment	750 participants
Start Date	2025-01-09
Primary Completion	2027-02-10 (estimated)
Study Completion	2028-10-18 (estimated)
Updated on ClinicalTrials.gov	2026-08-28