Flap Sparing in Postoperative Radiotherapy of Oral Cavity Cancers

Patients with oral cavity cancer treated by reconstructive surgery with a flap. Patients will be treated in the study for : * Experimental arm: Post-operative radiotherapy with flap sparing * Control arm: Standard post-operative radiotherapy without flap sparing (current practice) Radiotherapy by IMRT using photons or proton therapy (IMPT)

NCT Number	NCT06798922
Lead Sponsor	Centre Francois Baclesse
Conditions	Oral Cavity Carcinoma, Flap, Radiotherapy, Adjuvant, Reconstruction Surgery
Enrollment	348 participants
Start Date	2025-03-01
Primary Completion	2031-03-01 (estimated)
Study Completion	2034-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-22