Little NIRVANA for Pediatric Pain and Anxiety

The aim of this study is to test the feasibility of using Little NIRVANA (augmented reality (AR)) for managing anxiety and pain for children 2-8 years old during hospital emergency peripheral intravenous (PIV) insertions. The investigators hypothesize that Little NIRVANA plus a numbing cream will reduce pain and anxiety for patients undergoing PIV placement in the emergency department (ED) when compared to the cream alone. It is anticipated that using the Little NIRVANA will not increase the ED length of stay, failed PIV placement attempts, or the need for additional intervention.

NCT Number	NCT06795126
Lead Sponsor	Nationwide Children's Hospital Collaborators: KU Leuven, Health Resources and Services Administration (HRSA)
Conditions	Acute Pain, Procedural Anxiety, Pediatric ALL, Emergency Medicine, IV Access
Enrollment	130 participants
Start Date	2025-11-15
Primary Completion	2026-11-30 (estimated)
Study Completion	2027-08-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-11