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Multiple-biomarker Approach for Individualized Treatment of Heart Failure With Preserved Ejection Fraction

Study acronym: ADAPT-HFpEF
StatusActive, Not Recruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 2 months later Sep 1, 2026 → Nov 1, 2026
See other at-risk trials from Erasmus Medical Center

Record History

  1. Enrollment closed, study ongoing Primary and study completion pushed from Sep 1, 2026 to Nov 1, 2026 · Eligibility criteria expanded, about 13 words · Site details revised at 6 of 6 sites · 1 more Show 4 more changesShow less
    • Primary and study completion pushed from Sep 1, 2026 to Nov 1, 2026
    • Eligibility criteria expanded, about 13 words
    • Site details revised at 6 of 6 sites
    • Collaborators: details revised at 1 of 5 entries
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The primary objective is to investigate the association between temporal evolutions of blood biomarkers and clinical adverse events, in order to produce a dynamic, individual, and accurate prediction model for patients with HFpEF. Moreover several secondary objectives will be investigated.
Trial Details
NCT Number NCT06785506
Lead Sponsor Erasmus Medical Center
Collaborators: Ikazia Hospital, Rotterdam, Franciscus Gasthuis & Vlietland (Hospital), OLVG, Universitair Ziekenhuis Brussel, Noordwest Ziekenhuisgroep
Conditions Heart Failure With Preserved Ejection Fraction, Heart Failure, Diastolic, Chronic Heart Failure
Enrollment 200 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov