Clinical Trial

Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer

Not Yet Recruiting Phase 2
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Summary
This study is a single-arm, prospective, phase II clinical study to evaluate the efficacy and safety of preoperative short-course radiotherapy combined with ivonescimab and chemotherapy + total mesorectal excision(TME) surgery in patients with advanced rectal cancer.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-01-03.
Trial Details
NCT Number NCT06760520
Lead Sponsor The First Affiliated Hospital of Zhengzhou University
Conditions Locally Advanced Rectal Cancer
Enrollment 40 participants
Start Date 2025-01-20
Primary Completion 2027-12-20 (estimated)
Study Completion 2031-12-20 (estimated)
Updated on ClinicalTrials.gov 2025-01-08