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QL1706 Combined with Chemotherapy in the Treatment of Recurrent or Metastatic Endometrial Cancer

StatusNot Yet Recruiting
PhasePhase 2
Sponsorxiang yang
Started
View on ClinicalTrials.gov ↗

Record History

  1. Minor Study First Submitted
the investigators planned to evaluate the efficacy and safety of QL1706 in combination with chemotherapy as first-line systemic therapy in approximately 26 patients with newly diagnosed recurrent or metastatic endometrial cancer in a single-arm, open-label, multicenter study. The main questions it aims to answer are: Evaluate the efficacy and safety of QL1706 plus chemotherapy as first-line systemic therapy for recurrent or metastatic disease. According to the treatment regimen, a total of 26 subjects were enrolled. Eligible subjects received QL1706 (5mg/kg, Q3W, d1) plus carboplatin (AUC=5, Q3W, d1) plus paclitaxel (175mg/m2, Q3W, d1) for six to eight cycles at the investigator's discretion, followed by QL1706 (5mg/kg, Q3W, d1). d1) until disease progression, development of unacceptable toxicity, lack of benefit as judged by the investigator, withdrawal of consent, completion of 2 years of QL1706 treatment, or other reasons specified in the protocol.
Trial Details
NCT Number NCT06751277
Lead Sponsor xiang yang
Collaborators: Qilu Pharmaceutical Co., Ltd.
Conditions
(from sponsor)
Recurrent or Metastatic Endometrial Cancer
Related terms Endometrial Neoplasms, Recurrence
Enrollment 26 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov