Clinical Trial

A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China

Study acronym: CLM-tree datab

Recruiting

Summary

This is a retrospective and prospective study planned to include NSCLC patients with Leptomeningeal metastasis (LM) and treated with antitumor therapy after 2018, from multiple centers such as the First Affiliated Hospital of Guangzhou Medical University, Guangdong Sanjiu Brain Hospital, etc., aiming to establish a database related to the treatment strategies of LM patients, and to evaluate the efficacy (eg. Overall Survival/Time to Failure) and safety of different treatment strategies of LM patients, etc., as well as the significance of concomitant testing in LM patients.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2024-12-02.

Trial Details

NCT Number	NCT06718972
Lead Sponsor	Guangzhou Medical University
Conditions	Meningeal Metastasis, Non-Small Cell Lung Cancer
Enrollment	1,000 participants
Start Date	2024-09-01
Primary Completion	2028-12-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-04-27