Clinical Trial

A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and Drug-Drug Interaction Study of NX-5948 in Healthy Volunteers

Completed Phase 1
View on ClinicalTrials.gov →
Summary
This is a multiple part, multiple cohort study evaluating single and multiple ascending doses, relative bioavailability, food effect, and drug-drug interaction of NX-5948 in healthy volunteers.
Protocol Amendment History 6 changes
critical Trial completed 2026-07-29
critical Primary endpoint(s) modified 2026-07-29
notable Enrollment increased: 18 -> 223 participants 2026-07-29
minor Trial arms changed: 2 -> 7 2026-07-29
notable Primary completion pushed: 2026-04 -> 2026-05-01 2026-07-29
minor Completion moved earlier: 2026-08 -> 2026-05-01 2026-07-29
Trial Details
NCT Number NCT06717269
Lead Sponsor Nurix Therapeutics, Inc.
Conditions Healthy Volunteer
Enrollment 223 participants
Start Date 2024-11-30
Primary Completion 2026-05-01 (estimated)
Study Completion 2026-05-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-28