Skip to content
DataLookout
Start free
Menu

CACHENCT06706206

The CACHE Study: Coronary Artery Care in HaEmophilia

StatusActive, Not Recruiting
PhaseNot specified
Primary completion

At risk: Primary completion moved at least 5 months later.

See at-risk trials from Oxford University Hospitals NHS Trust

Track this trial

Free. We email you which fields changed when ClinicalTrials.gov updates this record.

Record History

All 5 versions: 4 with changes below, 1 re-verified with no change. See every version on ClinicalTrials.gov ↗

  1. Enrollment closed, study ongoing
    • Primary completion date changed from estimate of Jan 2027 to Nov 2, 2026
    • Site details revised
  2. Eligibility criteria expanded, about 10 words
    • Primary completion pushed from Jul 2026 to Jan 2027
    • Secondary endpoints: details revised at 2 of 2 entries
    • Study description revised
  3. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 0 to 1
    • Start date changed from estimate of Jan 2025 to Feb 25, 2025
    v2
  4. Study First Submitted
  • Notable: the plan changed
  • Minor: routine updates

Endpoints

Primary

Occurrence of coronary artery disease detected by coronary CT angiogram among people with haemophilia (PWH) versus control group.
Timeframe: Participant demographics and cardiovascular risk factors to be collected at enrolment for matching PWH and control group. Photon counting CCTA to be performed at enrolment for prevalence of CAD, and quantitative analyses in the secondary outcome.

Secondary (2)

Quantitative analysis of the volume of each plaque component (calcified, non-calcified, low-density plaques) among people with haemophilia (PWH) compared to control group.
Quantitative analysis of fat attenuation index (FAI) among PWH compared to control group.

Arms and interventions

Other: Observational trial

Sites

1 site in 1 country

  • Oxford Haemophilia and Thrombosis Centre, Oxford University Hospitals NHS Foundation TrustOxford, Oxfordshire, United Kingdom