This study is a placebo-controlled Phase I study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide (ASO) AMX0114 in adult participants with amyotrophic lateral sclerosis (ALS).
Protocol Amendment History
10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2024-10-28; most recent amendment 2026-04-09.
Status change: Not Yet Recruiting → Recruiting2025-02-05