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Vitamin C's Antioxidant Effects and COPD Prognosis

StatusNot Yet Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated December 17, 2024 (before its estimated February 28, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Notable Start date: Nov 20, 2024 to Dec 20, 2024v2
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
1,119 trials monitored
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This multicenter, randomized, double-blind, placebo-controlled clinical trial aims to evaluate the efficacy of Vitamin C supplementation in improving the prognosis of patients with Chronic Obstructive Pulmonary Disease (COPD) through its antioxidant effects. The primary objectives of the study are to determine: 1. Whether Vitamin C reduces the frequency of acute COPD exacerbations. 2. Whether Vitamin C improves pulmonary function and health-related quality of life in patients with COPD. The study will compare Vitamin C to a placebo to assess its impact on oxidative stress and its potential to enhance clinical outcomes in COPD management. Participants will: 1. Receive either daily oral Vitamin C supplementation or a placebo for a period of 6 months. Undergo monthly clinical evaluations, including spirometry and symptom assessments. 2. Report any adverse events or health changes during the trial.
Trial Details
NCT Number NCT06664957
Lead Sponsor Ningbo No. 1 Hospital
Conditions
(from sponsor)
COPD (Chronic Obstructive Pulmonary Disease)
Related terms Pulmonary Disease, Chronic Obstructive
Enrollment 650 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov