Clinical Trial

Expand Pulmonary Rehabilitation to Other Chronic Respiratory Diseases Than COPD

Study acronym: ExPuRe
Active, Not Recruiting
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Summary
The purpose of this pilot randomized clinical trial is to evaluate the willingness, acceptance, adherence and signs of benefits of structured home-based pulmonary rehabilitation (HPR) and supervised pulmonary tele-rehabilitation (PTR) on respiratory symptoms, quality of life, functioning and physical activity in patients with ILD (Interstitial lung disease, Idiopathic pulmonary fibrosis, Sarcoidosis), Bronchiectasis and Asthma who have a clinically assessed need for a pulmonary rehabilitation program. The main questions the project aims to answer are: * Will HPR and PTR appeal to a minimum of 30% of the eligble patients * Be greatly accepted (≥70% of participant complete 70% or more of the planned sessions) by patients agreeing to participate in the study * Will PTR and HPR lead to positive changes in respiratory symptom relief, symptom relief in general and improve or maintain physical functioning larger than usual care Researchers will compare with a comparable control group who gets usual care (scheduled controls and medication but no exercise intervention) to examine the willingness to be randomized and to get an indication on possible health related effects. Participants will be randomly assigned to one of three groups: 1. A structured supervised group-based PTR (exercise twice a week; each session consists of 35 min. evidence-based exercises and 25 min. of patient education) 2. An individual HPR program (self-initiated physical activity) with motivational and professional counseling once a week (10-15min), supported by a tablet screen 3. A control group receiving usual care (CON)
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2024-10-09; most recent amendment 2026-03-05.
Status change: Recruiting → Active, Not Recruiting 2026-03-05
Status change: Not Yet Recruiting → Recruiting 2024-10-30
Trial Details
NCT Number NCT06636487
Lead Sponsor Copenhagen University Hospital, Hvidovre
Collaborators: University Hospital Bispebjerg and Frederiksberg, Copenhagen University Hospital at Herlev, Nordsjaellands Hospital
Conditions Idiopathic Pulmonary Fibrosis (IPF), Sarcoidosis, Bronchiectasis, Asthma Bronchiale, Interstitial Lung Diseases (ILD)
Enrollment 50 participants
Start Date 2024-11-01
Primary Completion 2025-09-30 (estimated)
Study Completion 2027-05-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-09