Clinical Trial

Insulin Resistance and Coronary Microvascular Dysfunction in Patients with Myocardial Ischemia and Non-obstructive Coronary Artery Disease

Study acronym: IRIN
Recruiting
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Record status
This record was last updated September 19, 2024 (before its estimated June 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this prospective study is to assess the correlation between coronary microvascular disfunction and insulin resistance in patients with INOCA. Patients with ANOCA and without diabetes will undergo invasive coronary microvascular assessment through coronary angiography and insulin resistance assessment through hyperinsulinemic-euglycemic clamp test. Patients enrolled in the study will be followed for a period of 2 years to monitor their clinical status.
Trial Details
NCT Number NCT06597851
Lead Sponsor Azienda Ospedaliera Universitaria Integrata Verona
Conditions Coronary Microvascular Dysfunction, Coronary Microvascular Disease, Insulin Resistance
Enrollment 40 participants
Start Date 2024-06-24
Primary Completion 2025-06-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2024-09-19