Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.

The purpose of this research is to determine the safety and efficacy of withdrawing MMF (Mycophenolate Mofetil) in kidney transplant recipients who are 55 years or older at the time of receiving a kidney transplant. We are comparing them to patients who receive the standard of care Mycophenolate Mofetil.

NCT Number	NCT06568549
Lead Sponsor	Mayo Clinic Collaborators: Transplant Genomics, Inc., Eurofins
Conditions	Kidney Transplantation, Mycophenolate Mofetil
Enrollment	350 participants
Start Date	2025-06-13
Primary Completion	2030-12-31 (estimated)
Study Completion	2031-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-20