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Personalized Volume-deescalated Elective Nodal Irradiation in Oropharyngeal Head and Neck Squamous Cell Carcinoma

Study acronym: DeEscO
StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 7 months later Feb 28, 2029 → Sep 30, 2029
See other at-risk trials from University of Zurich

Record History

  1. Primary completion pushed from Feb 28, 2029 to Sep 30, 2029 Completion pushed from Feb 28, 2030 to Sep 30, 2030 · Eligibility criteria expanded, about 21 words · Secondary endpoints: details revised at 9 of 17 entries · 2 more Show 5 more changesShow less
    • Completion pushed from Feb 28, 2030 to Sep 30, 2030
    • Eligibility criteria expanded, about 21 words
    • Secondary endpoints: details revised at 9 of 17 entries
    • Collaborators: 5 to 6
    • Publications: details revised at 1 of 1 entry
  2. Study sites: 6 to 7v8
  3. Study sites: 5 to 6v7
  4. Study sites: 4 to 5v6
  5. Study sites: 3 to 4v5
Show 3 earlier versionsHide 3 earlier versions
  1. Study sites: 2 to 3v4
  2. Study sites: 1 to 2 Collaborators revised (5)v3 Show 1 more changeShow less
    • Collaborators revised (5)

    See this version in full on ClinicalTrials.gov ↗

  3. Trial status: Not Yet Recruiting to Recruiting Study sites: 0 to 1 · Primary completion date: Dec 1, 2028 to Feb 28, 2029 · Completion date: Dec 1, 2029 to Feb 28, 2030 · 1 morev2 Show 4 more changesShow less
    • Study sites: 0 to 1
    • Primary completion date: Dec 1, 2028 to Feb 28, 2029
    • Completion date: Dec 1, 2029 to Feb 28, 2030
    • Start date changed from estimate of Dec 1, 2024 to Feb 4, 2025
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Multicentric prospective model-based de-escalation of the elective clinical target volumes (CTV) in radiotherapy of oropharyngeal carcinoma of all stages with the goal to reduce toxicity. The study investigates the feasibility of this approach as measured by the number of expected out-of-field recurrencies based on the individual patient's state of disease progression and risk factors
Trial Details
NCT Number NCT06563362
Lead Sponsor University of Zurich
Collaborators: Insel Gruppe AG, University Hospital Bern, University Hospital, Geneva, Ospedale Regionale Bellinzona e Valli, Réseau Hospitalier Neuchâtelois, Kantonsspital Aarau, Kantonsspital Winterthur KSW
Conditions Oropharynx Cancer
Enrollment 120 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov