the Effect of Nutrition-optimized Prehabilitation on Perioperative Intervention in Primary Liver Carcinoma

The aim of this project is to investigate the effect of triple prehabilitation led by nutritional optimization in liver cancer patients' surgery. It improves the preoperative nutritional status of cancer patients, reduces the incidence of early postoperative complications, promotes postoperative recovery, and improves the quality of patients' survival. Patients were randomized into experimental and control groups based on exclusion and inclusion criteria. Nutritional interventions and exercise and psychological interventions for patients. Routine clinical blood tests will be performed at the time of enrollment, on the first day before surgery and on the first, third and fifth days after surgery. Enrolled patients were followed up by telephone or outpatient clinic at 1 month postoperatively.

NCT Number	NCT06549829
Lead Sponsor	Second Affiliated Hospital, Zhejiang University, School of Medicine Collaborators: ZhuZhou Central Hospital, Shangrao People's Hospital
Conditions	Hepatocellular Carcinoma, Liver Carcinoma, Hepatobiliary Cancers
Enrollment	120 participants
Start Date	2024-09-01
Primary Completion	2026-09-30 (estimated)
Study Completion	2026-10-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-12