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National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

Study acronym: RENOMICA-Hcor
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated May 8, 2026 (before its estimated August 31, 2026 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Enrollment increased: 600 → 1211 participants
    • Study sites revised (27)
    v4
  2. Study sites: 23 to 27
    • Primary and study completion dates: Dec 2026 to Aug 31, 2026
    • Start date changed from estimate of May 2025 to Apr 30, 2025
    v3
  3. Trial status: Not Yet Recruiting to Recruiting
    • Enrollment target: 1000 to 600
    • Start date: Oct 2024 to May 2025
    • Study sites: 1 to 23
    v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this observational study is to develop a registry of Brazilian patients with hereditary cardiovascular diseases, combining clinical and genomic data. The main questions it aims to answer are: Which genes are most commonly affected? What is the frequency of these genetic alterations in our population? Participants will be interviewed in routine medical care visits and their DNA will be sequenced.
Trial Details
NCT Number NCT06546137
Lead Sponsor Hospital do Coracao
Collaborators: Instituto Nacional de Cardiologia de Laranjeiras, Universidade Federal do Rio de Janeiro
Conditions
(from sponsor)		 Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated, Cardiomyopathy Restrictive, Arrhythmogenic Right Ventricular Dysplasia, Non-Compaction Cardiomyopathy, Familial Hypercholesterolemia, Marfan Syndrome, Ehlers-Danlos Syndrome, Vascular Type +6 more
Related terms Arrhythmogenic Right Ventricular Dysplasia, Brugada Syndrome, Cardiomyopathy, Dilated, Cardiomyopathy, Hypertrophic, Cardiomyopathy, Restrictive, Death, Sudden, Cardiac, Ehlers-Danlos Syndrome, Type IV, Hyperlipoproteinemia Type II, Loeys-Dietz Syndrome, Long QT Syndrome, Marfan Syndrome, Polymorphic Catecholaminergic Ventricular Tachycardia, Short Qt Syndrome
Enrollment 1,211 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov