Clinical Trial

Suicide Specific Rumination in Veterans

Completed

Summary

Few treatments target core features of suicidal thoughts and behaviors in Veterans. Real-time functional magnetic resonance imaging neurofeedback can provide information regarding brain activation associated with suicide-specific rumination, defined as a "repetitive mental fixation on one's suicidal thoughts and intentions." The goal of this feasibility study is for Veterans to learn strategies for modulating activity within brain regions that have been demonstrated to contribute to the maintenance of rumination, as they receive neurofeedback feedback signals from the brain.

Protocol Amendment History 3 changes

critical Trial completed 2026-08-11

notable Primary completion moved earlier: 2026-07-31 -> 2026-03-17 2026-08-11

minor Completion moved earlier: 2026-12-31 -> 2026-04-07 2026-08-11

Trial Details

NCT Number	NCT06481033
Lead Sponsor	VA Office of Research and Development
Conditions	Depression, Suicide, Mood Disorders
Enrollment	16 participants
Start Date	2024-08-01
Primary Completion	2026-03-17 (estimated)
Study Completion	2026-04-07 (estimated)
Updated on ClinicalTrials.gov	2026-08-10