UK CARDIOvascular Immune-Mediated Inflammatory Diseases (CARDIO-IMID) Registry Study

The goal of this observational study is to develop a large, deeply characterised cohort that will be a platform for collaborative clinical and translational research into cardiovascular (CV) disease (CVD) and Immune-mediated-inflammatory-diseases (IMID). The main aim is to evaluate whether existing blood cardiac biomarkers predict adverse cardiovascular outcomes. The study will capture standard of care CV and associated health data (clinical, biochemistry/pathology and investigations) in patients across the IMIDs. Optional biological and/or imaging sub-studies will provide additional data and/or samples for associated analyses.

NCT Number	NCT06478277
Lead Sponsor	University of Manchester Collaborators: University of Cambridge, University of Oxford, University of Edinburgh, University of Leeds, Imperial College London, Medical Research Council, British Heart Foundation, Swansea University, British Heart Foundation Data Science Centre
Conditions	Cardiovascular Diseases, Immune-Mediated Inflammatory Diseases
Enrollment	600 participants
Start Date	2026-02-04
Primary Completion	2028-08 (estimated)
Study Completion	2028-08 (estimated)
Updated on ClinicalTrials.gov	2026-02-06