Milk Thistle Clinical Trial in Pediatric NAFLD

Pediatric Fatty Liver disease is a growing problem in the United States and is expected to be the leading cause of Liver Transplantation in Adults in 20 years. Following lifestyle changes such as diet restrictions and exercise may be difficult to consistently maintain. The purpose of this study is to investigate alternative medical therapy with an herbal supplement called Milk Thistle (MT) which may improve fatty liver disease and would be easier to follow than diet and exercise.

NCT Number	NCT06477146
Lead Sponsor	University Hospitals Cleveland Medical Center
Conditions	Non-Alcoholic Fatty Liver Disease (NAFLD)
Enrollment	20 participants
Start Date	2024-12-19
Primary Completion	2029-01-31 (estimated)
Study Completion	2029-01-31 (estimated)
Updated on ClinicalTrials.gov	2026-01-27