Clinical Trial

Chest CT Biomarkers as Prognostic Predictors in SSc-ILD

Enrolling by Invitation
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Record status
This record was last updated September 11, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this retrospective observational study is to investigate whether novel imaging biomarkers of airways, vessels, and overall extent of fibrosis at baseline predict ILD progression, vasculopathy development, and survival in SSc-ILD.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-06-17.
Status change: Not Yet Recruiting → Enrolling by Invitation 2025-09-04
Trial Details
NCT Number NCT06472362
Lead Sponsor Royal Brompton & Harefield NHS Foundation Trust
Collaborators: Imperial College London, Royal Free and University College Medical School, The Leeds Teaching Hospitals NHS Trust, Hannover Medical School, University of Siena, Università Politecnica delle Marche, Azienda Ospedaliero Universitaria di Sassari, Bichat Hospital
Conditions Systemic Sclerosis
Enrollment 1,000 participants
Start Date 2024-11-01
Primary Completion 2025-12 (estimated)
Study Completion 2026-03-31 (estimated)
Updated on ClinicalTrials.gov 2025-09-11