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Novel Augmentation of DAOIB and Antioxidant for Early Dementia

Name: Novel Augmentation of DAOIB and Antioxidant for Early Dementia — clinical trial record (NCT06467539)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhasePhase 2

SponsorChang Gung Memorial Hospital

Started2024-06-19

View on ClinicalTrials.gov ↗

Amendment history

2026-03-18

Study Status v2

Re-verified, no change to tracked fields

2024-07-03

Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1

Trial statusNot Yet Recruiting→Recruiting

Start dateestimated 2024-06→confirmed 2024-06-19

Study sitesdetails revised at 1 of 1 site

2024-06-16

Original filing

Chang Gung Memorial Hospital

226 trials monitored

See 6 trials at risk

Alzheimer's Disease

1,140 trials monitored

See 62 trials at risk

Previous studies found that some NMDA-enhancing agents were able to improve cognitive function of patients with early-phase dementia. In addition, several drugs with antioxidant properties have been tested in clinical trials for the treatment of dementia too. Whether combined treatment of an NMDA-enhancing agent and a drug with antioxidant property can be better than an NMDA-enhancing agent alone deserves study.

Trial Details

NCT Number	NCT06467539
Lead Sponsor	Chang Gung Memorial Hospital
Conditions	Alzheimer Disease, Mild Cognitive Impairment
Enrollment	80 participants
Start Date	2024-06-19
Primary Completion	2027-05 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2026-03-19