Fluorouracil Treatment Via Colon for Colorectal Cancer

Fluorouracil (5-FU) is a commonly used drug for colorectal cancer (CRC). Thermosensitive hydrogel presents a promising carrier for 5-FU to address challenges encountered with traditional administration methods. We propose an integrated approach utilizing colonic transendoscopic enteral tubing to cover the entire colon flexibly, coupled with a thermo-sensitive gel to enhance the adhesion of 5-FU. This clinical trial aims to assess the feasibility, safety, and efficacy of this approach for treating CRC.

NCT Number	NCT06385418
Lead Sponsor	The Second Hospital of Nanjing Medical University
Conditions	Colorectal Cancer
Enrollment	40 participants
Start Date	2024-05-16
Primary Completion	2028-05-01 (estimated)
Study Completion	2029-05-01 (estimated)
Updated on ClinicalTrials.gov	2024-06-26