Clinical Trial

The PRO-FUTURE Project

Study acronym: PRO-FUTURE
Recruiting
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Record status
This record was last updated April 30, 2024 (before its estimated January 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to learn about specific biomarkers of unilateral ureteropelvic junction obstruction (UPJO) in children undergoing surgical intervention for unilateral UPJO compared with controls. The main question it aims to answer are: * Are Urinary single-cell and extracellular vesicles (EVs) screening useful to stage the intrarenal injury and repair processes in UPJO babies? * Do babies with unilateral UPJO have a whole blood gene expression profiling (WBGEP) allowing an accurate unilateral UPJO diagnosis?
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-04-19.
Trial Details
NCT Number NCT06382233
Lead Sponsor University of Campania Luigi Vanvitelli
Collaborators: University of Milan, A.O.R.N. Santobono-Pausilipon, University of Modena and Reggio Emilia, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Conditions Ureteropelvic Junction Obstruction, Chronic Kidney Diseases
Enrollment 85 participants
Start Date 2024-01-30
Primary Completion 2026-01-30 (estimated)
Study Completion 2028-01-30 (estimated)
Updated on ClinicalTrials.gov 2024-04-30