Clinical Trial

PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects

Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
The study will be conducted as an open-label and single-center study to evaluate the occupancy of ITI-1284 to the dopamine D2 receptor, serotonin 2A (5-HT2A) receptor, and serotonin transporter (SERT) in healthy subjects.
Protocol Amendment History 3 changes
minor Completion moved earlier: 2026-10-30 -> 2026-08-19 2026-08-01
notable Primary completion pushed: 2026-07 -> 2026-07-31 2026-07-07
minor Completion pushed: 2026-07 -> 2026-10-30 2026-07-07
Trial Details
NCT Number NCT06299410
Lead Sponsor Intra-Cellular Therapies, Inc.
Conditions Healthy Volunteers
Enrollment 42 participants
Start Date 2024-04-11
Primary Completion 2026-08-19 (estimated)
Study Completion 2026-08-19 (estimated)
Updated on ClinicalTrials.gov 2026-07-31