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Behavioral Activation for the Treatment of Depression in Older Adults

Study acronym: DepActive
StatusRecruiting
PhaseNot applicable
Started
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Trial flagged as At Risk
Enrollment reduced 68% 250 → 81 participants
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Record History

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  1. Notable Enrollment reduced: 250 → 81 participants Show 7 more changesShow less
    • Recruitment opened
    • Primary completion moved earlier from Dec 31, 2027 to Nov 15, 2026
    • Study completion moved earlier from Dec 31, 2028 to Nov 15, 2026
    • Study sites: 1 to 2
    • Secondary endpoints: details revised at 7 of 8 entries
    • Publications: details revised at 4 of 4 entries
    • Eligibility criteria expanded, about 4 words
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
3,055 trials monitored
See 173 trials at risk
Depression affects between 5-15% of adults ≥ 65 years in Sweden. Depression in older adults reduces functional ability and quality of life, and increases the risk for morbidity, loneliness, and suicide. Psychological treatment is recommended as a first-line treatment for depression, which about 3% of older adults with depression in Sweden report receiving. One effective psychological treatment is behavioral activation, which reduces depressive symptoms by increasing enjoyable, meaningful and important activities, for example exercise and social activities. The research group conducted a pilot study of telephone based behavioral activation for isolated older adults with depression during the COVID-19 pandemic. The intervention consisted of four telephone calls, and the results showed a significant decrease in depressive symptoms, with maintained effects for six months. 250 individuals will participate in the study. Half of the participants will be randomised to start the intervention immediately, while the other half of the participants will be randomized to a control group receiving treatment as usual at their respective primary care center. Participants will be asked to fill in questionnaires before, after treatment. Questionnaires will also be sent 3- and 6 months after treatment to follow up on the results. Patients will be asked to wear an accelerometer for 5-7 days to record their activity level at baseline, post-intervention and after 3-months. A smaller group of participants (10-15) will be asked to participate in a more detailed interview about how they experienced the treatment.
Trial Details
NCT Number NCT06284889
Lead Sponsor Uppsala University
Collaborators: Västmanland County Council, Sweden, Sormland County Council, Sweden, Uppsala County Council, Sweden
Conditions
(from sponsor)
Depression
Related terms Depression, Motor Activity
Enrollment 81 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov