Clinical Trial

New Treatment of Cardiac Device Infections; Immediate Reimplantation After Removal of Infected System

Study acronym: POET-PPM
Recruiting Phase 3
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Summary
The goal of this randomized clinical trials is to ascertain the safety and efficacy of immediate reimplantation of cardiac electronic implantable devices in patients with endocarditis and device-infections, compared to standard care, i.e. reimplantation at a later procedure date. The primary outcome is the occurence of the composite primary endpoint within 6 months of randomization consisting of * Death * Symptomatic embolism (systemic arterial embolism or pulmonary embolism) * Bacteremia og pocket-infection * Removal of a CIED due to new infection
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-02-01; most recent amendment 2025-10-06.
Trial Details
NCT Number NCT06250985
Lead Sponsor Rigshospitalet, Denmark
Conditions Endocarditis, Bacterial
Enrollment 176 participants
Start Date 2024-04-29
Primary Completion 2027-12-31 (estimated)
Study Completion 2037-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-10-08