Clinical Trial

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

Active, Not Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The study consists of a randomized double-masked, placebo-controlled, parallel-group, multicenter trial with an optional open-label treatment period for proptosis non-responders who complete the Double-masked Treatment Period.
Protocol Amendment History 1 change
minor Completion pushed: 2026-09-02 -> 2026-11-13 2026-07-08
Trial Details
NCT Number NCT06248619
Lead Sponsor Amgen
Conditions Thyroid Eye Disease
Enrollment 89 participants
Start Date 2024-07-05
Primary Completion 2025-12-23 (estimated)
Study Completion 2026-11-13 (estimated)
Updated on ClinicalTrials.gov 2026-07-07