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A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

Name: A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors — clinical trial record (NCT06244485)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusActive, Not Recruiting

PhasePhase 1

SponsorDaiichi Sankyo

Started2024-02-22

View on ClinicalTrials.gov ↗

This study will evaluate the safety, tolerability, and efficacy of valemetostat tosylate in combination with DXd antibody-drug conjugates (ADC) in participants with advanced solid tumors.

Amendment history 4 changes detected by DataLookout

2026-09-16

Enrollment increased: 98 → 210 participants

2026-07-22

Trial status changed: Recruiting → Active, Not Recruiting

2026-07-22

Enrollment reduced: 210 → 98 participants

2026-07-22

Trial sites reduced: 38 → 35 locations

Trial Details

NCT Number	NCT06244485
Lead Sponsor	Daiichi Sankyo
Conditions	Advanced Solid Tumor
Enrollment	210 participants
Start Date	2024-02-22
Primary Completion	2028-11-01 (estimated)
Study Completion	2028-11-01 (estimated)
Updated on ClinicalTrials.gov	2026-09-15